Dr. Michael
F. Roizen
“The science of plasma exchange isn’t new. What’s new is bringing it to the people who need it most — before disease takes hold.”
Publications
#1 Ranked
Published
One of America’s most recognized voices in preventive medicine.
Dr. Michael Roizen is co-founder of Lifespan Edge, a platform scaling therapeutic plasma exchange for the next generation of longevity clinics. Alongside entrepreneur John Mauldin, he’s bringing one of medicine’s most clinically established therapies to patients who want to get ahead of aging — not just manage it.
Dr. Roizen served as founding chair of its Wellness Institute — the first such role at a major U.S. healthcare institution — and has spent his career translating cutting-edge science into tools real people can use. He has authored more than 188 peer-reviewed publications and co-authored four #1 New York Times bestsellers, reaching millions of readers in 44 languages worldwide.
A Phi Beta Kappa graduate of Williams College and Alpha Omega Alpha graduate of UCSF School of Medicine, he completed his residency at Harvard’s Beth Israel Hospital and his Public Health Service at the NIH in the laboratory of Nobel Prize winner Julius Axelrod.
“Therapeutic plasma exchange is not experimental medicine. It is established medicine being applied with new intentionality — to patients who are well enough to get ahead of the biology that will eventually make them unwell.”
— Dr. Michael F. Roizen, MD · Co-Founder, Lifespan EdgeThe therapy existed. The platform to scale it didn’t.
Dr. Roizen has spent his career at the intersection of rigorous science and practical access. Therapeutic plasma exchange has decades of clinical history. What’s been missing is a structure that brings it to motivated, health-forward patients — before chronic disease takes hold.
Evidence-backed. The AMBAR study and decades of apheresis literature underpin every treatment protocol at Lifespan Edge.
Preventive, not reactive. The goal is intervening while patients are well — not waiting for disease markers to force action.
Scalable access. Lifespan Edge is building the infrastructure to bring TPE beyond major academic medical centers.
188+ peer-reviewed publications. Four #1 bestsellers.
A career translating science into tools real people can use.
Notes on prevention, longevity, and getting ahead of aging.
Research breakdowns, clinical observations, and essays on the science of living longer, better.
A new study in Obesity suggests GLP-1s dosed every two weeks — rather than weekly — can retain effectiveness at significantly lower cost. What that means for patients trying to reach a goal weight and hold it.
Read the essay →Three new studies converge on the same answer for cognitive decline: coffee consumption, a lithium mechanism, and brain-training for processing speed each appear to cut dementia risk meaningfully. A rundown of what the data actually shows.
Read the breakdown →Most New Year’s resolutions don’t make it past February. The fix isn’t more discipline — it’s better architecture. A look at the systems that actually hold when motivation fades.
Read the letter →Ready to get ahead of aging?
Dr. Roizen and the Lifespan Edge team are available for consultations at our Frisco, Dallas, and El Dorado Hills locations.