Therapeutic Plasma Exchange
Clinics open nationwide.
Stay sharp, stay resilient, and keep the energy for what you love with plasmapheresis protocols developed by Dr. Michael Roizen.
Your biology is unique. Your protocol should be too.

Where will you start?
Find your clinic.
Lifespan Edge brings longevity medicine to clinics nationwide, with more on the way. Our care is built on Dr. Roizen’s longevity framework, delivered in calm, restorative settings.
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Dallas, Texas
Minutes from The Star in Frisco
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West Palm Beach, Florida
Minutes from downtown West Palm Beach.
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Columbia, Maryland
Minutes from downtown Columbia.
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Dorado Beach, Puerto Rico
Minutes from Dorado Beach.
How It Works
Longevity starts with a call.
Book a free call
Thirty minutes to talk through what you want your next years to feel like.
Choose your clinic
We’ll help match you to the location and care that fit your lifestyle.
Begin
Your clinical team builds your plan, and your longevity work starts that day.
Your Care
Designed by Dr. Michael Roizen.
Every Lifespan Edge protocol is tailored to your unique physiology and built from Dr. Roizen’s longevity framework — the same evidence-based approach he has spent his career refining.
- Creator of the RealAge methodology
- Four-time #1 New York Times bestselling author
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Dr. Michael Roizen
From Our Patients
Real patients. Real transformation.
“I haven’t felt this good in years.”Richard · Dallas Clinic
“I felt incredible after my very first treatment.”Song · Dallas Clinic
FAQS
Questions, answered.
What is Therapeutic Plasma Exchange?
TPE filters your blood to remove inflammatory proteins, damaged molecules, and other pro-aging factors that accumulate over time, then replaces them with clean replacement fluid. Think of it as changing the oil in your engine — clearing out the biological waste your body can no longer filter on its own.
Is TPE established medicine, or is it experimental?
Plasma exchange has been used in hospitals for decades. The American Society for Apheresis (ASFA) recognizes therapeutic apheresis across 66 conditions and 111 indications. What’s newer is the research into its role in longevity and cognitive health — including the AMBAR trial, which studied plasma exchange in patients with moderate Alzheimer’s disease.
What happens at my first visit?
Your first step is a comprehensive blood panel and a physician assessment. From there, your clinical team designs a protocol tailored to your physiology and goals — no two plans are identical.
How long does a session take?
A typical in-clinic plasma exchange session takes about 90 minutes. Many patients describe the experience as calm and restful, and most return to their day afterward.
Which clinic should I choose?
Start with a free discovery call. We’ll talk through your goals, your lifestyle, and the locations nearest you, then help you choose the clinic that fits. You can also explore each clinic’s page for hours, directions, and what to expect.
Your next chapter starts with a
conversation.
Book thirty minutes with our clinical team to explore whether Lifespan Edge is right for you.